Antiviral Responses of Tissue-resident CD49a+ Lung Natural Killer Cells Are Dysregulated in Chronic Obstructive Pulmonary Disease
- Creator: Cooper, Grace E. , Mayall, Jemma , Khakoo, Salim I. , Wilkinson, Tom M. A. , Hansbro, Philip M. , Staples, Karl J. , Donovan, Chantal , Haw, Tatt J. , Budden, Kurtis F. , Hansbro, Nicole G. , Blomme, Evy E. , Maes, Tania , Kong, Chia Wei , Horvat, Jay C.
- Resource Type: journal article
- Date: 2023
Characterization and inhibition of inflammasome responses in severe and non-severe asthma
- Creator: Horvat, Jay C. , Kim, Richard Y. , Weaver, Natasha , Augood, Christopher , Brown, Alexandra C. , Donovan, Chantal , Dupre, Pierrick , Gunawardhana, Lakshitha , Mayall, Jemma R. , Hansbro, Nicole G. , Robertson, Avril A. B. , O'Neill, Luke A. J. , Cooper, Matthew A. , Holliday, Elizabeth G. , Hansbro, Philip M. , Gibson, Peter G.
- Resource Type: journal article
- Date: 2023
RIPK1 kinase-dependent inflammation and cell death contribute to the pathogenesis of COPD
- Creator: Van Eeckhoutte, Hannelore P. , Donovan, Chantal , Beal, Allison M. , Geddes, Brad , Bertin, John , Vanden Berghe, Tom , De Volder, Joyceline , Maes, Tania , Vandenabeele, Peter , Vanaudenaerde, Bart M. , Deforce, Dieter , Škevin, Sonja , Kim, Richard Y. , Van Nieuwerburgh, Filip , Verhamme, FM , Joos, GF , Idrees, S , Schiller, HB , Yildirim, AÖ , Faiz, A , Bertrand, MJM , Brusselle, GG , Hansbro, Philip M. , Conlon, Thomas M. , Bracke, KR , Ansari, Meshal , Khan, Haroon , Jayaraman, Ranjith , Hansbro, Nicole G. , Dondelinger, Yves , Delanghe, Tom
- Resource Type: journal article
- Date: 2023
TLR7 promotes smoke-induced experimental lung damage through the activity of mast cell tryptase
- Creator: Liu, Gang , Haw, Tatt Jhong , Hortle, Elinor , Pickles, Sophie , Rojas-Quintero, Joselyn , Estepar, Raul San Jose , Marshall, Jacqueline E. , Kim, Richard Y. , Collison, Adam M. , Mattes, Joerg , Idrees, Sobia , Faiz, Alen , Starkey, Malcolm R. , Hansbro, Nicole G. , Fukui, R , Murakami, Y , Cheng, HS , Tan, NS , Chotirmall, SH , Horvat, Jay C. , Foster, Paul S. , Oliver, BG , Polverino, F , Philp, Ashleigh M. , Ieni, A , Monaco, F , Caramori, G , Sohal, SS , Bracke, KR , Wark, Peter A. , Adcock, IM , Miyake, K , Sin, DD , Hansbro, Philip M. , Pavlidis, Stelios , Nalkurthi, Christina , Nair, Prema M. , Gomez, Henry M. , Hanish, Irwan , Hsu, Alan CY
- Resource Type: journal article
- Date: 2023
Adverse roles of mast cell chymase-1 in chronic obstructive pulmonary disease
- Creator: Liu, Gang , Jarnicki, Andrew G. , Paudel, Keshav R. , Lu, Wenying , Wadhwa, Ridhima , Philp, Ashleigh M. , Van Eeckhoutte, Hannelore , Marshall, Jacqueline E. , Malyla, Vamshikrishna , Katsifis, Angelica , Fricker, Michael , Hansbro, Nicole G. , Dua, Kamal , Kermani, Nazanin Z. , Eapen, Mathew S. , Tiotiu, Angelica , Chung, K. Fan , Caramori, Gaetano , Bracke, Ken , Adcock, Ian M. , Wark, Peter A. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2022
Adverse roles of mast cell chymase-1 in COPD
- Creator: Liu, Gang , Jarnicki, Andrew G. , Fricker, Michael , Hansbro, Nicole G. , Dua, Kamal , Kermani, Nazanin Z. , Eapen, Mathew S. , Tiotiu, Angelica , Chung, K. Fan , Caramori, Gaetano , Bracke, Ken , Adcock, Ian M. , Paudel, Keshav R. , Sohal, Sukhwinder S. , Wark, Peter A. , Oliver, Brian G. , Hansbro, Philip M. , Lu, Wenying , Wadhwa, Ridhima , Philp, Ashleigh M. , Van Eeckhoutte, Hannelore , Marshall, Jacqueline E. , Malyla, Vamshikrishna , Katsifis, Angelica
- Resource Type: journal article
- Date: 2022
Increased SARS-CoV-2 Infection, Protease, and Inflammatory Responses in Chronic Obstructive Pulmonary Disease Primary Bronchial Epithelial Cells Defined with Single-Cell RNA Sequencing
- Creator: Johansen, Matt D. , Mahbub, Rashad M. , Gallego-Ortega, David , Britton, Warwick J. , Saunders, Bernadette M. , Wark, Peter A. , Faiz, Alen , Hansbro, Philip M. , Idrees, Sobia , Nguyen, Duc H. , Miemczyk, Stefan , Pathinayake, Prabuddeha , Nichol, Kristy , Hansbro, Nicole G. , Gearing, Linden J. , Hertzog, Paul J.
- Resource Type: journal article
- Date: 2022
A monoclonal antibody to Siglec-8 suppresses non-allergic airway inflammation and inhibits IgE-independent mast cell activation
- Creator: Schanin, Julia , Gebremeskel, Simon , Evensen, Erik , Brock, Emily C. , Xu, Alan , Wong, Alan , Leung, John , Bebbington, Christopher , Tomasevic, Nenad , Youngblood, Bradford A. , Korver, Wouter , Falahati, Rustom , Butuci, Melina , Haw, Tatt Jhong , Nair, Prema M. , Liu, Gang , Hansbro, Nicole G. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2021
The complex interplay between endoplasmic reticulum stress and the NLRP3 inflammasome: a potential therapeutic target for inflammatory disorders
- Creator: Chong, Wai Chin , Shastri, Madhur D. , Peterson, Gregory M. , Patel, Rahul P. , Pathinayake, Prabuddha S. , Dua, Kamal , Hansbro, Nicole G. , Hsu, Alan C. , Wark, Peter A. , Shukla, Shakti Dhar , Johansen, Matt D. , Schroder, Kate , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2021
Antiproliferative effects of boswellic acids-loaded chitosan nanoparticles on human lung cancer cell line A549
- Creator: Solanki, Neeta , Mehta, Meenu , Hansbro, Philip M. , Dua, Kamal , Dureja, Harish , Chellappan, Dinesh Kumar , Gupta, Gaurav , Hansbro, Nicole G. , Tambuwala, Murtaza M. , Aljabali, Alaa Aa , Paudel, Keshav Raj , Liu, Gang , Satija, Saurabh
- Resource Type: journal article
- Date: 2020
Celastrol-loaded liquid crystalline nanoparticles as an anti-inflammatory intervention for the treatment of asthma
- Creator: Chan, Yinghan , Ng, Sin Wi , Chellappan, Dinesh Kumar , Madheswaran, Thiagarajan , Zeeshan, Farrukh , Kumar, Pradeep , Pillay, Viness , Gupta, Gaurav , Wadhwa, Ridhima , Mehta, Meenu , Wark, Peter , Hsu, Alan , Hansbro, Nicole G. , Hansbro, Philip Michael , Dua, Kamal , Panneerselvam, Jithendra
- Resource Type: journal article
- Date: 2020
Curcumin-loaded niosomes downregulate mRNA expression of pro-inflammatory markers involved in asthma: an in vitro study
- Creator: Wong, Jin-Ying , Ng, Zhao Yin , Hsu, Alan , Hansbro, Nicole G. , Wark, Peter , Bebawy, Mary , Hansbro, Philip Michael , Dua, Kamal , Chellappan, Dinesh Kumar , Mehta, Meenu , Shukla, Shakti D. , Panneerselvam, Jithendra , Madheswaran, Thiagarajan , Gupta, Gaurav , Negi, Poonam , Kumar, Pradeep , Pillay, Viness
- Resource Type: journal article
- Date: 2020
Elastin is a key factor of tumor development in colorectal cancer
- Creator: Li, Jinzhi , Xu, Xiaoyue , Jiang, Yanyan , Hansbro, Nicole G. , Hansbro, Philip M. , Xu, Jincheng , Liu, Gang
- Resource Type: journal article
- Date: 2020
Emerging concepts and directed therapeutics for the management of asthma: regulating the regulators
- Creator: Shastri, Madhur , Chong, Wai Chin , Hansbro, Philip M. , Dua, Kamal , Peterson, Gregory M. , Patel, Rahul P. , Mahmood, Malik Q. , Tambuwala, Murtaza , Chellappan, Dinesh K. , Hansbro, Nicole G. , Shukla, Shakti D.
- Resource Type: journal article
- Date: 2020
Human beta-defensin-2 suppresses key features of asthma in murine models of allergic airways disease
- Creator: Pinkerton, James W. , Kim, Richard Y. , Nordkild, Peter , Horvat, Jay C. , Jensen, Benjanim A. H. , Wehkamp, Jan , Hansbro, Philip M. , Koeninger, Louis , Armbruster, Nicole S. , Hansbro, Nicole G. , Brown, Alexandra C. , Jayaraman, Ranjith , Shen, Sijie , Malek, Nisar , Cooper, Matthew A.
- Resource Type: journal article
- Date: 2020
Lipopolysaccharide induces steroid-resistant exacerbations in a mouse model of allergic airway disease collectively through IL-13 and pulmonary macrophage activation
- Creator: Hadjigol, Sara , Netto, Keilah G. , Maltby, Steven , Tay, Hock L. , Nguyen, Thi H. , Hansbro, Nicole G. , Eyers, Fiona , Hansbro, Philip M. , Yang, Ming , Foster, Paul S.
- Resource Type: journal article
- Date: 2020
Plants derived therapeutic strategies targeting chronic respiratory diseases: chemical and immunological perspective
- Creator: Prasher, Parteek , Sharma, Mousmee , Wich, Peter R. , Hansbro, Nicole G. , Hansbro, Philip M. , Dua, Kamal , Mehta, Meenu , Paudel, Keshav R. , Satija, Saurabh , Chellappan, Dinesh K. , Dureja, Harish , Gupta, Gaurav , Tambuwala, Murtaza M. , Negi, Poonam
- Resource Type: journal article
- Date: 2020
Role of Lung Microbiome in Innate Immune Response Associated With Chronic Lung Diseases
- Creator: Paudel, Keshav Raj , Dharwal, Vivek , Yang, Ian A. , Kohonen-Corish, Maija R. J. , Bebawy, Mary , Dua, Kamal , Hansbro, Philip M , Patel, Vyoma K. , Galvao, Izabela , Wadhwa, Ridhima , Malyla, Vamshikrishna , Shen, Sj Sijie , Budden, Kurtis F. , Hansbro, Nicole G. , Vaughan, Annalicia
- Resource Type: journal article
- Date: 2020
Solid lipid nanoparticles containing anti-tubercular drugs attenuate the Mycobacterium marinum infection
- Creator: Khatak, Sunil , Mehta, Meenu , Awasthi, Rajendra , Paudel, Keshav Raj , Singh, Sachin Kumar , Gulati, Monica , Hansbro, Nicole G. , Hansbro, Philip M. , Dua, Kamal , Dureja, Harish
- Resource Type: journal article
- Date: 2020
Fibulin-1c regulates transforming growth factor-beta activation in pulmonary tissue fibrosis
- Creator: Liu, Gang , Cooley, Marion A. , Jones, Berrnadette , Hansbro, Nicole G. , Wark, Peter A. , Horvat, Jay C. , Argraves, W. Scott , Oliver, Brian G. , Knight, Darryl A. , Burgess, Janette K. , Hansbro, Philip M. , Jarnicki, Andrew G. , Borghuis, Theo , Nair, Prema M. , Tjin, Gavin , Hsu, Alan C. , Haw, Tatt Jhong , Fricker, Michael , Harrison, Celeste L.
- Resource Type: journal article
- Date: 2019